A New DUB Makes Linear Ubiquitin a Party to Its Own Destruction
نویسندگان
چکیده
منابع مشابه
A New DUB Makes Linear Ubiquitin a Party to Its Own Destruction
Linear ubiquitin (Ub) plays a role in nuclear factor κB signaling, but the deubiquitinating enzyme that disassembles these chains was unknown. In this issue of Cell, Keusekotten et al. identify a new enzyme that disassembles linear chains with the use of a mechanism that relies on Ub itself to help catalyze peptide bond cleavage.
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ژورنال
عنوان ژورنال: Cell
سال: 2013
ISSN: 0092-8674
DOI: 10.1016/j.cell.2013.05.018